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The circular dichroism effect characterized by different optical responses between left-handed and right-handed circularly polarized lights is widely applied for biological monitoring, analytical chemistry, and plasmonic sensing. Despite the fact that circular dichroisms are achieved by many conventional chiral and anisotropic metamaterials, dynamic and efficient modulation of circular dichroisms is still challenging. In this paper, we demonstrate a VO _2 embedded metamaterial enabling tunable chirality by taking advantages of the VO _2 phase transitions between insulators and metals. Specifically, by changing the laser power and the irradiated position on the metamaterial, the VO _2 phase transition takes place at the irradiated region and induces a tunable circular dichroism effect. This work provides a strategy for the active control and modulation of circular polarizations, which pays the way for applications in terahertz and microwave regions.