Pro-BNP Levels and Its Prognostic Role in Chronic Hypertensive Pregnancies: A Prospective Case-Control Study From A Tertiary Care Hospital
oleh: Mehmet Akif Erdol, Atakan Tanacan, Hasan Eroglu, Nazan Vanli Tonyali, Mehmet Erdogan, Aykan Yucel, Nuray Yazihan, Dilek Sahin
| Format: | Article |
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| Diterbitkan: | Taylor & Francis Group 2021-07-01 |
Deskripsi
Background: This study aimed to investigate the prognostic value of N-terminal B-type natriuretic peptide (NT-proBNP) in pregnancies with isolated chronic hypertension (HT). Method: 34 pregnant women with chronic HT and 40normotensive controls were enrolled. The association between plasma NT-proBNP levels obtained in the first trimester and perinatal complications were evaluated. Results: NT-proBNP levelsstrongly predicted low birth weight (AUC=0.842, p<0.001). NT-proBNP and birth weight were negatively correlated (r= -0.323, p=0.005). NT-proBNP was found to be an individual determinant of low birth weight in univariate analysis (OR:1.03; 95%CI:1.01-1.04). Conclusion: NT-proBNP levels can be useful to predict low birth weight in pregnancies with chronic HT.