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Coronavirus are single standard enveloped RNA virus and gets its name from Latin meaning “crown” as envelope of this virus appears crown-like under electron microscopy. The coronavirus has few importance structural proteins that include spike (S), envelope (E), membrane (M) and nucleocapsid (N). Virus commonly infects birds & mammals causing gastroenteritis and respiratory infection ranging from common cold to SARS-COV (Severe Acute Respiratory Syndrome-Associated Coronavirus) and MERS-COV (Middle-East respiratory syndrome) [1].