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Mastocytosis is a group of a disorder characterized by infiltration of mast cell in various organs, e.g. skin, bone marrow, liver, spleen, gastrointestinal tract, lymph node, etc., The term bullous mastocytosis is generally used to describe the varieties of mastocytosis manifested with predominantly cutaneous vesico-bullous lesions and the more commonly represents the diffuse cutaneous form. We report a case of diffuse cutaneous mastocytosis (bullous mastocytosis) in a 6-month-old child.