Single cell transcriptome analysis of developing arcuate nucleus neurons uncovers their key developmental regulators
oleh: Christian Huisman, Hyeyoung Cho, Olivier Brock, Su Jeong Lim, Sung Min Youn, Younjung Park, Sangsoo Kim, Soo-Kyung Lee, Alessio Delogu, Jae W. Lee
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2019-08-01 |
Deskripsi
Despite the crucial physiological processes governed by neurons in the hypothalamic arcuate nucleus (ARC), the developmental pathways and regulators for ARC neurons remain understudied. In this study the authors use single cell RNA-seq analyses of mouse embryonic ARC to identify cell type-specific markers for developing ARC neurons and give key insight into the underlying developmental pathways and regulators.