An anionic ligand snap-locks a long-range interaction in a magnesium-folded riboswitch

oleh: Rajeev Yadav, Julia R. Widom, Adrien Chauvier, Nils G. Walter

Format: Article
Diterbitkan: Nature Portfolio 2022-01-01

Deskripsi

A single molecule fluorescence study revealed three dynamically interconverting conformations of the fluoride riboswitch from Bacillus cereus, where an anionic ligand snap-locks a docked conformation through a long-range interaction necessary for downstream gene regulation.