Modelling the Tox21 10 K chemical profiles for in vivo toxicity prediction and mechanism characterization
oleh: Ruili Huang, Menghang Xia, Srilatha Sakamuru, Jinghua Zhao, Sampada A. Shahane, Matias Attene-Ramos, Tongan Zhao, Christopher P. Austin, Anton Simeonov
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2016-01-01 |
Deskripsi
Large-scale in vitro assays may reduce the number of toxicological tests carried out in animals. Here, Huang et al. report a large dataset containing results of in vitrotests of approximately 10,000 chemicals, and use these data to create models that can potentially predict toxicity in humans.