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In the current framework, a computational simulation for 2-D γ−AL2O3 nanofluid flow over a stretching surface with Marangoni convection embedded in porous medium is presented. Here the magnetic field and nonlinear thermal radiation is also applied with heat source/sink. A comparative analysis is presented for water and ethylene glycol based γ−AL2O3 nanofluids. A mathematical model of the present problem with appropriate boundary conditions is given in terms of partial differential equations. Numerical calculation of this model is computed by the Runge-Kutta method of order four with shooting technique by utilizing the suitable similarity transformations. Temperature and velocity fields are studied analytically and illustrated by the graphs for various flow control parameters. Results shows that the temperature profile of the γ−Al2O3−H2O nanofluid is always higher than the γ−Al2O3−C2H6O2 nanofluid hence γ−Al2O3−C2H6O2 nanofluid becomes more significant in cooling process then γ−Al2O3−H2O nanofluid.