MICU1 controls cristae junction and spatially anchors mitochondrial Ca2+ uniporter complex
oleh: Benjamin Gottschalk, Christiane Klec, Gerd Leitinger, Eva Bernhart, René Rost, Helmut Bischof, Corina T. Madreiter-Sokolowski, Snježana Radulović, Emrah Eroglu, Wolfgang Sattler, Markus Waldeck-Weiermair, Roland Malli, Wolfgang F. Graier
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2019-08-01 |
Deskripsi
Proper mitochondrial structure is critical for normal function. Here, the authors show with SIM that the mitochondrial Ca2+ uniporter complex and localization of component MICU1 is critical to maintaining cristae junction stability and overall mitochondrial membrane structure.