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The retinal disease is one of the most important challenges in the field of ophthalmology. Its pathogenesis is complex and has a great damage to visual functional. It is the main cause of severe human vision. In recent years, the development of artificial intelligence(AI)is a powerful tool for analytics of retinal diseases. The application of AI to common retinal diseases mainly includes early screening, diagnostic grading, efficacy determination, treatment suggestions and prognostic development. However, any technology clinical application has its limitations. This article will be reviewed for the application of AI in retinal diseases.