Enhancer and super-enhancer dynamics in repair after ischemic acute kidney injury

oleh: Julia Wilflingseder, Michaela Willi, Hye Kyung Lee, Hannes Olauson, Jakub Jankowski, Takaharu Ichimura, Reinhold Erben, M. Todd Valerius, Lothar Hennighausen, Joseph V. Bonventre

Format: Article
Diterbitkan: Nature Portfolio 2020-07-01

Deskripsi

Acute kidney injury is a major health problem amongst hospitalized patients. Here the authors provide a comprehensive characterization of enhancer and super-enhancer elements, and the transcription factor motifs associated with these elements in response to kidney injury in vivo; providing insight into the regulation of kidney repair.