AKAP95 regulates splicing through scaffolding RNAs and RNA processing factors

oleh: Jing Hu, Alireza Khodadadi-Jamayran, Miaowei Mao, Kushani Shah, Zhenhua Yang, Md Talat Nasim, Zefeng Wang, Hao Jiang

Format: Article
Diterbitkan: Nature Portfolio 2016-11-01

Deskripsi

The chromatin-associated protein AKAP95 is known for its chromatin-related functions including enhancing transcription. Here the authors show that AKAP95 interacts with the splicing regulatory factors as well as RNAs to regulate the inclusion of exons and pre-mRNA splicing.