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AKAP95 regulates splicing through scaffolding RNAs and RNA processing factors
oleh: Jing Hu, Alireza Khodadadi-Jamayran, Miaowei Mao, Kushani Shah, Zhenhua Yang, Md Talat Nasim, Zefeng Wang, Hao Jiang
Format: | Article |
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Diterbitkan: | Nature Portfolio 2016-11-01 |
Deskripsi
The chromatin-associated protein AKAP95 is known for its chromatin-related functions including enhancing transcription. Here the authors show that AKAP95 interacts with the splicing regulatory factors as well as RNAs to regulate the inclusion of exons and pre-mRNA splicing.