Non-invasive molecularly-specific millimeter-resolution manipulation of brain circuits by ultrasound-mediated aggregation and uncaging of drug carriers
oleh: Mehmet S. Ozdas, Aagam S. Shah, Paul M. Johnson, Nisheet Patel, Markus Marks, Tansel Baran Yasar, Urs Stalder, Laurent Bigler, Wolfger von der Behrens, Shashank R. Sirsi, Mehmet Fatih Yanik
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2020-10-01 |
Deskripsi
Non-invasive manipulation of brain circuits with molecular and spatial specificity could revolutionize the treatment of brain disorders. Here, the authors remotely concentrate and deliver drugs to focal brain regions without compromising the blood-brain barrier using novel ultrasound sequences and drug carriers.