Phenotypic and Genotypic Adaptations in Pseudomonas aeruginosa Biofilms following Long-Term Exposure to an Alginate Oligomer Therapy
oleh: Juliette L. Oakley, Rebecca Weiser, Lydia C. Powell, Julian Forton, Eshwar Mahenthiralingam, Philip D. Rye, Katja E. Hill, David W. Thomas, Manon F. Pritchard
| Format: | Article |
|---|---|
| Diterbitkan: | American Society for Microbiology 2021-02-01 |
Deskripsi
The emergence of multidrug-resistant (MDR) pathogens within biofilms in the cystic fibrosis lung results in increased morbidity. An inhalation therapy derived from alginate, OligoG CF-5/20, is currently in clinical trials for cystic fibrosis patients.