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Gastro-intestinal (GI) perforation and subsequent septic diffused peritonitis are the most common life-threatening condition in dogs and cats. The common predisposing factors for gastroduodenal ulcers leading to perforations include NSAID administration, hepatic disease, major surgery, periods of high stress, shock, and other causes of decreased gastric circulation, gastric hyperacidity, and gastrointestinal neoplasia (Willard, 1995 and Sullivan and Yool, 1998). Perforations are also caused due to foreign body ingestion, gastric dilatationand volvulus, external trauma, leakage of previous enterotomy or anastomotic sites, and perforation ofjejunum, ileum, or colon. (Hinton et al., 2002). The present paper deals with a case of gastric perforation in a dog.