A cryptic third active site in cyanophycin synthetase creates primers for polymerization
oleh: Itai Sharon, Sharon Pinus, Marcel Grogg, Nicolas Moitessier, Donald Hilvert, T. Martin Schmeing
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-07-01 |
Deskripsi
Cyanophycin synthetase CphA1 polymerizes Asp and Arg into the nitrogen reserve polymer cyanophycin using two active sites. Sharon et al. show CphA1 has a cryptic 3rd active site that cleaves cyanophycin into primers for self-sufficient biosynthesis.