Efficient organocatalytic multicomponent synthesis of (α-aminoalkyl)phosphonates

oleh: Suresh Maddila, Satya Kumar Avula, Anil Kumar Avula, Palakondu Lavanya

Format: Article
Diterbitkan: Elsevier 2016-11-01

Deskripsi

l-Proline has been used as an organocatalyst for an efficient synthesis of (α-aminoalkyl) phosphonates by treatment of aldehydes, amines and triethyl phosphate at room temperature. The products are formed in excellent yields (82–94%) within 30–45 min.