Genome-wide association analysis and replication in 810,625 individuals with varicose veins

oleh: Waheed-Ul-Rahman Ahmed, Sam Kleeman, Michael Ng, Wei Wang, Adam Auton, 23andMe Research Team, Regent Lee, Ashok Handa, Krina T. Zondervan, Akira Wiberg, Dominic Furniss

Format: Article
Diterbitkan: Nature Portfolio 2022-06-01

Deskripsi

Although varicose veins are a common condition, the genetic basis is not well understood. Here, the authors find genetic variants associated with varicose veins and show that a higher polygenic risk score for varicose veins correlates with a greater likelihood of patients undergoing surgical treatment.