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Wetting of bentonite is a complex hydro-mechanical process that involves swelling and, if confined, significant structural changes in its void structure. A coupled structural transport network model is proposed to investigate the effect of wetting of bentonite on retention conductivity and swelling pressure response. The transport network of spheres and pipes, representing voids and throats, respectively, relies on Laplace–Young’s equation to model the wetting process. The structural network uses a simple elasto-plastic approach without hardening to model the rearrangement of the fabric. Swelling is introduced in the form of an eigenstrain in the structural elements, which are adjacent to water filled spheres. For a constrained cell, swelling is shown to produce plastic strains, which result in a reduction of pipe and sphere spaces and, therefore, influence the conductivity and retention behaviour.