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Taking into account that nowadays emergencies and reemergencies of infectious diseases exist, fundamentally in tropical areas, it is necessary to advice  health professionals and health authorities, about the threat that represents the  Zika virus. To such effects an exhaustive literature review was carried out where some aspects of interest are analyzed, such as: vectors and pouches, transmission ways, clinical features, differential diagnosis and treatment, among others,  which will help to increase the knowledge level in this respect and be prepared to face any epidemic disease of this nature.