Integration of epigenetic and genetic profiles identifies multiple sclerosis disease-critical cell types and genes
oleh: Qin Ma, Hengameh Shams, Alessandro Didonna, Sergio E. Baranzini, Bruce A. C. Cree, Stephen L. Hauser, Roland G. Henry, Jorge R. Oksenberg
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2023-03-01 |
Deskripsi
The combined analysis of single cell and bulk epigenetic datasets and multiple sclerosis GWAS reveals the enrichment of genetic susceptibility signals in B cells and monocyte-microglia cell types.