Apolipoprotein J is a hepatokine regulating muscle glucose metabolism and insulin sensitivity
oleh: Ji A Seo, Min-Cheol Kang, Won-Mo Yang, Won Min Hwang, Sang Soo Kim, Soo Hyun Hong, Jee-In Heo, Achana Vijyakumar, Leandro Pereira de Moura, Aykut Uner, Hu Huang, Seung Hwan Lee, Inês S. Lima, Kyong Soo Park, Min Seon Kim, Yossi Dagon, Thomas E. Willnow, Vanita Aroda, Theodore P. Ciaraldi, Robert R. Henry, Young-Bum Kim
| Format: | Article |
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| Diterbitkan: | Nature Portfolio 2020-04-01 |
Deskripsi
Hepatokines are proteins secreted by the liver that can regulate whole body metabolism. Here the authors identify apolipoprotein J as a hepatokine that regulates muscle glucose metabolism and insulin resistance through a low-density lipoprotein receptor-related protein−2 mediated mechanism in mice.