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Objective: to evaluate the effect of COVID-19 on the development of endocrine pathology in the studied adult patientsMaterials and methods: Clinical and laboratory studies were conducted in 166 patients aged 18-65 years with a confirmed diagnosis of coronavirus infection U07.1 (COVID-19); with moderate (140 patients) and severe (26 patients) course of the disease. The control group included 35 practically healthy individuals aged 18 to 65 years.Results: In the acute period of COVID-19; the development of subclinical hypothyroidism; low T3 syndrome; subclinical thyrotoxicosis; as well as hypoand hypercortisolemia was revealed. 6 months after discharge from the hospital on an outpatient basis; the development of thyroid pathology in 6 patients and diabetes mellitus in 5 patients was revealed in COVID-19 convalescents.