Secondary hemophagocytic lymphohistiocytosis due to nivolumab/ipilimumab in a renal cell cancer patient—A case report

oleh: Adeel Masood, Ahsan Wahab, Tanya Clifford, Eric J. Weaver, Hamid Ehsan, Walid El Ayass

Format: Article
Diterbitkan: Wiley 2021-12-01

Deskripsi

Abstract Secondary immune‐related hemophagocytic lymphohistiocytosis is a rare but life‐threatening complication of immune checkpoint inhibitors. HLH‐2004 and HLH‐1994 guidelines originally developed for primary HLH are the only available guidelines. It has proven to have a good prognosis if diagnosed promptly with discontinuation of immunotherapy and treated with corticosteroid monotherapy.