FAM222A encodes a protein which accumulates in plaques in Alzheimer’s disease

oleh: Tingxiang Yan, Jingjing Liang, Ju Gao, Luwen Wang, Hisashi Fujioka, The Alzheimer Disease Neuroimaging Initiative, Xiaofeng Zhu, Xinglong Wang

Format: Article
Diterbitkan: Nature Portfolio 2020-01-01

Deskripsi

In this study the authors identify a possible link between the gene FAM222A and brain atrophy. The protein it encodes is found to accumulate in plaques seen in Alzheimer’s disease, and functional analysis suggests it interacts with amyloid-beta.