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<p/> <p>We consider the fourth-order two-point boundary value problem <inline-formula> <graphic file="1687-2770-2010-570932-i1.gif"/></inline-formula>, <inline-formula> <graphic file="1687-2770-2010-570932-i2.gif"/></inline-formula>, <inline-formula> <graphic file="1687-2770-2010-570932-i3.gif"/></inline-formula>, where <inline-formula> <graphic file="1687-2770-2010-570932-i4.gif"/></inline-formula> is a parameter, <inline-formula> <graphic file="1687-2770-2010-570932-i5.gif"/></inline-formula> is given constant, <inline-formula> <graphic file="1687-2770-2010-570932-i6.gif"/></inline-formula> with <inline-formula> <graphic file="1687-2770-2010-570932-i7.gif"/></inline-formula> on any subinterval of <inline-formula> <graphic file="1687-2770-2010-570932-i8.gif"/></inline-formula>, <inline-formula> <graphic file="1687-2770-2010-570932-i9.gif"/></inline-formula> satisfies <inline-formula> <graphic file="1687-2770-2010-570932-i10.gif"/></inline-formula> for all <inline-formula> <graphic file="1687-2770-2010-570932-i11.gif"/></inline-formula>, and <inline-formula> <graphic file="1687-2770-2010-570932-i12.gif"/></inline-formula>, <inline-formula> <graphic file="1687-2770-2010-570932-i13.gif"/></inline-formula>, <inline-formula> <graphic file="1687-2770-2010-570932-i14.gif"/></inline-formula> for some <inline-formula> <graphic file="1687-2770-2010-570932-i15.gif"/></inline-formula>. By using disconjugate operator theory and bifurcation techniques, we establish existence and multiplicity results of nodal solutions for the above problem.</p>