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Microwave-promoted solvent-free synthesis of para-quinone methides (p-QMs) derivatives
oleh: Zhang-Qin Liu, Peng-Sheng You, Chuan-Hua Wu, Yang-Hong Han
Format: | Article |
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Diterbitkan: | Elsevier 2020-01-01 |
Deskripsi
A rapid and efficient methodology for the synthesis of polysubstituted para-quinone methides (p-QMs) from aldehyde and 2,6-di-tert-butylphenol has been achieved in solvent-free and microwave irradiation condition within 33 min. This strategy displays the advantages including high atom economy, good functional group tolerance, and environmentally friendly operation. Keywords: Para-Quinone methides (p-QMs), Green chemistry, Microwave irradiation, Environment friendly synthesis