Microwave-promoted solvent-free synthesis of para-quinone methides (p-QMs) derivatives

oleh: Zhang-Qin Liu, Peng-Sheng You, Chuan-Hua Wu, Yang-Hong Han

Format: Article
Diterbitkan: Elsevier 2020-01-01

Deskripsi

A rapid and efficient methodology for the synthesis of polysubstituted para-quinone methides (p-QMs) from aldehyde and 2,6-di-tert-butylphenol has been achieved in solvent-free and microwave irradiation condition within 33 min. This strategy displays the advantages including high atom economy, good functional group tolerance, and environmentally friendly operation. Keywords: Para-Quinone methides (p-QMs), Green chemistry, Microwave irradiation, Environment friendly synthesis