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Biohydrogen is a source of renewable and clean energy. Many countries are working to generate biohydrogen energy as a means of combating the present global warming trend. This review paper aims to highlight the available information on hydrogen production from municipal solid waste biomass and also highlight several factors influencing the rate of biohydrogen production and their challenges in the future. The study of hydrogen production processes was aimed at a complete understanding of modern hydrogen production technologies, both implemented in practice and under research or development. The review revealed some advantages of biological methods for producing hydrogen gas compared to chemical ones. Also, this paper identified different factors that affect the biohydrogen production process such as type of bioreactors, temperature, pH, light, nutrients. This study also brings to the surface the challenges that need attention from researchers