Single-cell transcriptomics of human iPSC differentiation dynamics reveal a core molecular network of Parkinson’s disease
oleh: Gabriela Novak, Dimitrios Kyriakis, Kamil Grzyb, Michela Bernini, Sophie Rodius, Gunnar Dittmar, Steven Finkbeiner, Alexander Skupin
| Format: | Article |
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| Diterbitkan: | Nature Portfolio 2022-01-01 |
Deskripsi
Gabriela Novak et al. utilize scRNA-seq to investigate expression profiles in iPSC-derived midbrain dopaminergic neurons from Parkinson’s disease patients or healthy controls. Their results suggest a core molecular network associated with Parkinson’s disease pathology, and provide a future resource for investigation of this critical disorder.