A mosquito salivary protein promotes flavivirus transmission by activation of autophagy
oleh: Peng Sun, Kaixiao Nie, Yibin Zhu, Yang Liu, Pa Wu, Ziwen Liu, Senyan Du, Huahao Fan, Chun-Hong Chen, Renli Zhang, Penghua Wang, Gong Cheng
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2020-01-01 |
Deskripsi
Mosquito saliva affects transmission of flaviviruses, but underlying mechanisms are incompletely understood. Here, the authors show that Aedes aegypti venom allergen-1 (AaVA-1) promotes dengue and Zika virus transmission by activating autophagy in host immune cells of the monocyte lineage.