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Statin Utilization Patterns among Type 2 Diabetes Mellitus Patients with High Cardiovascular Disease Risks in Ethiopia
oleh: Tsegaye Melaku, Yordanos Solomon, Legese Chelkeba
Format: | Article |
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Diterbitkan: | Research Center for Rational Use of Drugs (RCRUD) 2019-07-01 |
Deskripsi
Background: Cardiovascular disease is a leading cause of morbidity and mortality among type 2 diabetes mellitus (T2DM) patients. It has been proved & recommended by most guidelines that statins are effective for primary or secondary cardiovascular diseases prophylaxis. The aim of the study was to assess the pattern of statin use among T2DM patients with high risk of cardiovascular diseases. Methods: Hospital-based cross-sectional study was conducted among T2DM patients from February to April 2018 at Jimma University Medical Center. Patient-specific data including clinical characteristics, laboratory work ups and medication records were collected using a structured data collection tool. Results: Mrom a total of 150 study participants, 93(62%) of them were males. Majority of the patient, 112(74.7%), were between age of 40-64 years (mean ± SD of 46.65±19.61 years). About 55(36.67%) of participants were on statin therapy for treatment & prophylaxis. Age between 65 to 74 years (AOR = 3.006; 95% CI: 1.440–6.277; P=0.003), disease co-morbidity (AOR 4.486; 95% CI: 2.080–9.673; P<0.001) & elevated blood cholesterol (AOR = 1. 422; 95% CI: 1.244–1.622; P=0.033), living with diabetes mellitus for more than 10 years (AOR=2.45; 95% CI: 1.524- 3.891; P=0.027) & uncontrolled blood sugar (AOR=2.127; 95% CI: 1.833–2.457; P=0.0241) were independent predictor of statin use. Conclusion: The majority of patients with type 2 diabetes were not receiving statins. Further interventions to improve statin use should be considered for these high-risk patients