Prevalence of G2P[4] and G12P[6] Rotavirus, Bangladesh
oleh: Mustafizur Rahman, Rasheda Sultana, Giasuddin Ahmed, Sharifun Nahar, Zahid M. Hassan, Farjana Saiada, Goutam Podder, Abu S. G. Faruque, A. K. Siddique, David A. Sack, Jelle Matthijnssens, Marc Van Ranst, Tasnim Azim
| Format: | Article |
|---|---|
| Diterbitkan: | Centers for Disease Control and Prevention 2007-01-01 |
Deskripsi
Approximately 20,000 stool specimens from patients with diarrhea visiting an urban and a rural hospital in Bangladesh during January 2001–May 2006 were tested for group A rotavirus antigen, and 4,712 (24.0%) were positive. G and P genotyping was performed on a subset of 10% of the positive samples (n = 471). During the 2001–2005 rotavirus seasons, G1P[8] (36.4%) and G9P[8] (27.7%) were the dominant strains, but G2[4] and G12P[6] were present in 15.4% and 3.1% of the rotavirus-positive patients, respectively. During the 2005–06 rotavirus season, G2P[4] (43.2%) appeared as the most prevalent strain, and G12P[6] became a more prevalent strain (11.1%) during this season. Because recently licensed rotavirus vaccines are specific for only P[8], these vaccines may not perform well in settings where non-P[8] types are prevalent.