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Background: Hypothyroidism (especially subclinical hypothyroidism) and Metabolic Syndrome (MetS) association have been controversial. Aim and Objectives: This study was aimed to examine the MetS components in patients with Clinical and Subclinical Hypothyroidism (CH & SCH) in northeast Iran. Material and Methods:In this cross-sectional study, 186 hypothyroid patients were evaluated for MetS using NCEP-ATP III criteria. Thyroid function and lipid profile parameters were measured using ELISA and enzymatic photometric methods. Results: MetS was common in 53.2% of hypothyroid patients. The odds of MetS in 50 years and above were about 3.2 times higher than those under 50 (p = 0.001). Simple logistic regression analysis showed decreasing one mg/dl High-Density Lipoprotein Cholesterol (HDL-C) increased nearly 10% odds of MetS (OR = 0.916; 95% CI: 0.882–0.951; p = 0.001). In addition, rising one unit Waist Circumference (WC) increased about 14% odds of MetS (OR = 1.137; 95% CI: 1.092–1.183; p = 0.001).As well as, multiple logistic regression analysis showed low HDL-C (p = 0.0001), high SBP (p = 0.0001), and high WC (p = 0.009) had the most significant effect on developing MetS, respectively. Conclusion: This study determined that CH and SCH are significantly associated with MetS. In addition, MetS significantly increased in reduced HDL-C, increased SBP, and age more than 50.