A transcomplementing gene drive provides a flexible platform for laboratory investigation and potential field deployment

oleh: Víctor López Del Amo, Alena L. Bishop, Héctor M. Sánchez C., Jared B. Bennett, Xuechun Feng, John M. Marshall, Ethan Bier, Valentino M. Gantz

Format: Article
Diterbitkan: Nature Portfolio 2020-01-01

Deskripsi

Gene drives raise safety concerns around unintended propagation. Here the authors present a trans-complementing split-gene drive that requires inheritance of separate transgenes to assemble a fully functional drive.