Intracellular construction of topology-controlled polypeptide nanostructures with diverse biological functions

oleh: Li-Li Li, Sheng-Lin Qiao, Wei-Jiao Liu, Yang Ma, Dong Wan, Jie Pan, Hao Wang

Format: Article
Diterbitkan: Nature Portfolio 2017-11-01

Deskripsi

The intracellular topology of a nanostructure plays a major role in its interactions with the cell and accordingly, its biological applications. Here, the authors design peptides that intracellularly polymerize into elastin-like polypeptides and assemble into various topologies, each of which exhibits a distinct set of biological functions.