Find in Library
Search millions of books, articles, and more
Indexed Open Access Databases
Resilience and Vulnerability to Pain and Inflammation in the Hippocampus
oleh: Verica Vasic, Mirko H. H. Schmidt
Format: | Article |
---|---|
Diterbitkan: | MDPI AG 2017-03-01 |
Deskripsi
Increasing evidence demonstrates the importance of hippocampal neurogenesis, a fundamental mechanism of neuroplasticity associated with cognition and emotion, in correlation to neurodegenerative and psychiatric disorders. Neuropsychiatric disorders are often a result of chronic stress or pain followed by inflammation; all these conditions manifest cognitive deficits and impairments in neurogenesis. However, while some individuals are more susceptible to stress, others are able to adapt to new environments via mechanisms of resilience. In light of this emerging field and based on extensive research, the role of neurogenesis is summarized and presented as a potentially powerful therapeutic tool.