Structure of Epstein-Barr virus tegument protein complex BBRF2-BSRF1 reveals its potential role in viral envelopment
oleh: Hui-Ping He, Meng Luo, Yu-Lu Cao, Yu-Xin Lin, Hua Zhang, Xiao Zhang, Jun-Ying Ou, Bing Yu, Xiaoxue Chen, Miao Xu, Lin Feng, Mu-Sheng Zeng, Yi-Xin Zeng, Song Gao
| Format: | Article |
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| Diterbitkan: | Nature Portfolio 2020-10-01 |
Deskripsi
Epstein-Barr virus (EBV) tegument proteins BBRF2 and BSRF1 have been suggested to form a hetero-complex. Here, He et al. provide the crystal structures of BBRF2 alone and in complex with BSRF1 and suggest that the complex tethers EBV nucleocapsids to the Golgi membrane, facilitating secondary envelopment.