Quantitative optical nanophysiology of Ca2+ signaling at inner hair cell active zones

oleh: Jakob Neef, Nicolai T. Urban, Tzu-Lun Ohn, Thomas Frank, Philippe Jean, Stefan W. Hell, Katrin I. Willig, Tobias Moser

Format: Article
Diterbitkan: Nature Portfolio 2018-01-01

Deskripsi

Quantitatively studying components of the presynapse requires high resolution optical methods. Here the authors use confocal microscopy as well as 2D- and 3D-STED nanoscopy to quantify the number and activity of active zone Ca2+ channels in inner hair cells.