Progressive divisions of multipotent neural progenitors generate late-born chandelier cells in the neocortex

oleh: Khadeejah T. Sultan, Wenying Angela Liu, Zhao-Lu Li, Zhongfu Shen, Zhizhong Li, Xin-Jun Zhang, Owen Dean, Jian Ma, Song-Hai Shi

Format: Article
Diterbitkan: Nature Portfolio 2018-11-01

Deskripsi

Diverse GABAergic neurons arise from progenitors in the medial ganglionic eminence. Here, the authors show these progenitors are progressively fate-restricted, with early-born interneurons occupying cortex in an “inside-out” pattern and later-born types like chandelier cells generated “outside-in”.