New types of MYST3-CBP and CBP-MYST3 fusion transcripts in t(8;16)(p11;p13) acute myeloid leukemias

oleh: Anne Murati, José Adélaïde, Benoît Quilichini, Virginie Rémy, Danielle Sainty, Anne-Marie Stoppa, Philippe Bernard, Sylviane Olschwang, Daniel Birnbaum, Max Chaffanet, Marie-Joëlle Mozziconacci

Format: Article
Diterbitkan: Ferrata Storti Foundation 2007-02-01

Deskripsi

The t(8;16)(p11;p13) translocation, associated with poor prognosis acute monocytic leukemia, fuses MYST3 on chromosome region 8p11 to CBP on chromosome region 16p13. Two types of MYST3-CBP and CBP-MYST3 fusion transcripts have been identified in patients. We describe two new types of MYST3-CBP transcripts and a new primer set.