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The application of artificial intelligence in the field of biomedicine is accelerating, showing broad prospects in public health, clinical diagnosis and health management. However, it will also cause many potential and existing ethical dilemmas. At present, the ethical issues that are attractive are: 1) the moral status of artificial intelligence; 2) fairness issues caused by artificial intelligence applications; 3) the contradiction between individual rights and public interests. This paper a discussed the above issues. From a balanced point of view, several principles are proposed for discussion and challenges from the academic community.