Cell-free fetal DNA testing and its correlation with prenatal indications
oleh: Jing-wei Wang, Yong-nan Lyu, Bin Qiao, Yan Li, Yan Zhang, Pavan Kumar Dhanyamraju, Yevgeniya Bamme, Michael D. Yu, Dongqin Yang, Yong-qing Tong
| Format: | Article |
|---|---|
| Diterbitkan: | BMC 2021-08-01 |
Deskripsi
Highlights The whole-genome sequencing of cell-free fetal DNA from maternal plasma is an effective prenatal screening tool for pregnancies with various prenatal indications. The concentration of cffDNA was linear with gestational age and the Z-score values of the positive NIPT group. NIPT has a significant positive predictive value for pregnancies with prenatal indications.