Network heterogeneity regulates steering in actin-based motility
oleh: Rajaa Boujemaa-Paterski, Cristian Suarez, Tobias Klar, Jie Zhu, Christophe Guérin, Alex Mogilner, Manuel Théry, Laurent Blanchoin
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2017-09-01 |
Deskripsi
Protrusive cellular structures contain a heterogeneous density of actin, but whether this influences motility is not known. Using an in vitro system and modelling, here the authors show that local actin monomer depletion and network architecture can tune the rate of network growth to impose steering during motility.