Antimicrobial protein REG3A regulates glucose homeostasis and insulin resistance in obese diabetic mice
oleh: Patrick Gonzalez, Alexandre Dos Santos, Marion Darnaud, Nicolas Moniaux, Delphine Rapoud, Claire Lacoste, Tung-Son Nguyen, Valentine S. Moullé, Alice Deshayes, Gilles Amouyal, Paul Amouyal, Christian Bréchot, Céline Cruciani-Guglielmacci, Fabrizio Andréelli, Christophe Magnan, Jamila Faivre
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2023-03-01 |
Deskripsi
Antimicrobial protein REG3A improved insulin sensitivity by combating oxidative stress and activating AMPK in skeletal muscle in HFD-induced obese mice overexpressing human REG3A in the liver.