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Abstract Background Lens dislocation is a common disease in ophthalmology, which leads to vision loss, while the lens dislocation caused by vomiting has not been reported yet. We report a case of lens dislocation caused by simple vomiting. This case further implicated for the pathogenesis of lens dislocation. Case presentation A 51-year-old male who complained about “dizziness, vomiting, and the vision decreased for 4 h in right eye”, after the eye examination, he was been diagnosed with “lens dislocation induced by simply vomiting “. Surgery was performed successfully.We highlight the pathogenesis and development of the lens dislocation in this rare condition. Conclusion Lens dislocation could be induced by simple vomitting, which increased the vitrous cavity presure to shock the zonular fiber and push the lens into the anterior chamber.