S8-mediated decarboxylative cyclization of 2-nitrophenols with arylacetic acid: Synthesis of benzoxazoles

oleh: Haifeng Gan, Dalong Yang

Format: Article
Diterbitkan: Elsevier 2019-11-01

Deskripsi

A concise, metal-free protocol has been established for the preparation of 2-arylbenzoxazoles from 2-nitrophenols and arylacetic acids via a sulfur-mediated redox decarboxylative cyclization reaction. The reactions proceeded in moderate to good yields, and gram-scale is suitable. Keywords: Benzoxazoles, Arylacetic acid, Decarboxylation, Cyclization, Elemental sulfur