A role for Dynlt3 in melanosome movement, distribution, acidity and transfer
oleh: Zackie Aktary, Alejandro Conde-Perez, Florian Rambow, Mathilde Di Marco, François Amblard, Ilse Hurbain, Graça Raposo, Cédric Delevoye, Sylvie Coscoy, Lionel Larue
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-03-01 |
Deskripsi
Aktary et al. identify novel roles for the dynein light chain Dynlt3 in melanosome transport, maturation, and transfer to keratinocytes. They also find that the Wnt/βcatenin signalling pathway controls Dynlt3 levels and thus also contributes to the regulation of melanocyte transport and skin pigmentation.