P113 is a merozoite surface protein that binds the N terminus of Plasmodium falciparum RH5
oleh: Francis Galaway, Laura G. Drought, Maria Fala, Nadia Cross, Alison C. Kemp, Julian C. Rayner, Gavin J. Wright
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2017-02-01 |
Deskripsi
The secretedPlasmodium falciparum protein RH5 is essential for invasion of erythrocytes and is a promising vaccine candidate. Here, Galaway et al. show that the N-terminal region of RH5 binds the GPI-anchored merozoite surface protein P113 and can elicit invasion-blocking antibodies.