Engineering of a bona fide light-operated calcium channel
oleh: Lian He, Liuqing Wang, Hongxiang Zeng, Peng Tan, Guolin Ma, Sisi Zheng, Yaxin Li, Lin Sun, Fei Dou, Stefan Siwko, Yun Huang, Youjun Wang, Yubin Zhou
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-01-01 |
Deskripsi
Existing optogenetic methods to induce calcium mobilisation lack selectivity and specificity. Here, the authors design and engineer a single-component light-operated calcium channel to provide optical control over calcium signals and calcium-dependent physiological responses: LOCa.