Quantitative single-cell live imaging links HES5 dynamics with cell-state and fate in murine neurogenesis
oleh: Cerys S. Manning, Veronica Biga, James Boyd, Jochen Kursawe, Bodvar Ymisson, David G. Spiller, Christopher M. Sanderson, Tobias Galla, Magnus Rattray, Nancy Papalopulu
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2019-06-01 |
Deskripsi
The single-cell gene expression changes during spinal cord formation and neurogenesis in mice are unclear. Here, the authors use a HES5 reporter to live image, then mathematically model, oscillations in single cells in presumed progenitors and neurons of the developing spinal cord.